To study the effects of hydrocephalus and skull defect on the pressure volume index(PVI), PVI values were measured in 4 groups, total 23 cats. Five normal cats(group I : control group), five kaolin induced hydrocephalic cats(group II), six kaolin
induced hydrocephalic cats with delayed hemicranicetomy(group III) and seven kaolin induced hydrocephalic-hemicraniectomy cats(group IV) were used. In 4 groups, the effects of laterality of ventricular bolus infusion site, hydrocephalus and skull
defect
on the PVI values were evaluated. The measuremnets were performed 4 weeks after kaolin injection in hydrocephalic groups(group II, III and IV). The laterality of infusion site did not have statistically significant influence on the PVI value in
all
4
groups. Compared to group I, the PVI values in group II and III showed increasing tendency without significance. But in group IV, the PVI values showed statistically significant increase, and this seemed to be due to the biomechanical changes of
brain
and the more progressive ventricular enlargement by the combination of kaolin induced hydrocephalus and skull defect. As with above results. PVI values showed increasing tendency according to the degree of ventricular enlargement and the defect
of
skull.
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